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state, the intracellular compartment is 70 to 90 mV negative (the resting membrane potential) Electrical discharge of neural and muscular tissue is predicated on a special property of excitable membranes namely, that the permeability of the cell to Na is controlled by the electrical potential of the membrane As the membrane is depolarized by any slight electrical or chemical change, there is an increased permeability to Na The subsequent movement of K outward repolarizes the membrane and thereby reduces its permeability to Na If a greater degree of depolarization occurs, a situation arises in which the outward movement of K is unable to stabilize the membrane potential The membrane then becomes even more depolarized and progressively more permeable to Na, and an explosive, or regenerative Na current develops; sodium rushes down its chemical and electrical gradients into the cell With the elevation in Na permeability, the Na ions would continue to depolarize the intracellular compartment to about 40 mV (the Nernst equilibrium potential for Na) Indeed, it is this depolarization of the intracellular compartment, lasting a few milliseconds, that constitutes the action potential However, an equilibrium is not established, because there is a rapid (within 5 ms) fall in membrane Na permeability back to baseline levels This fall in Na permeability occurs because the initial depolarization inactivates the Na conductance The transient depolarization at the same time activates an increase in membrane permeability to K The combined effects of the resulting ef ux of K and a diminishing in ux of Na repolarizes the membrane to a resting level During a brief period immediately after repolarization, the nerve and muscle bers are refractory, at rst absolutely then relatively, to another depolarizing stimulus The duration of the refractory period is determined largely by the duration of the inactivation of the Na channel Conduction, or propagation of the action potential along excitable nerve or muscle membranes, occurs as the current ows into the contiguous membrane, which in turn becomes depolarized When the depolarization reaches the threshold for development of an action potential, a new zone of increased Na permeability is created In this manner, the action potential then spreads in an allor-none fashion, down the length of the nerve or muscle membrane (see Kuf er et al for further details) The action potentials in individual nerve bers are too small and brief to be detected by conventional nerve conduction techniques, but a summated volley of all the bers comprised by a nerve is large enough to be recorded, and it is this property that is utilized to study nerve function in the clinical electromyography (EMG) laboratory As the motor nerve impulses pass centrifugally from the axon into its terminal branches, transmission may still break down, especially if the repetition rate is excessive and impulses arrive too frequently at branch points Impulses may then fail to reach the myoneural junction of these bers; or there may be failure of con-.

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6 A The maximum capacity of an SRAM chip is 256KB Its technology precludes it from supporting higher capacities in a single chip DRAM, on the other hand, is able to support much larger capacities B, 512KB, C, 1MB, and D, 64MB, are all incorrect SRAM chips cannot be made to hold more than 256KB A DRAM is used as main memory because it is cheaper than SRAM It also supports higher capacities than SRAM However, DRAM draws more power from the computer because it requires a constant refresh, and it is not nearly as fast as SRAM B is incorrect because it states that SRAM is used as main memory because it is faster than DRAM Although it is true that SRAM is faster, it is not used as main memory due to its expense and its relatively low capacity per chip (256KB) C, which states that DRAM is used as cache memory because it is available in higher capacities than SRAM, is also incorrect SRAM is used as cache memory because of its speed Although SRAM is limited in capacity, most systems do not improve when more than 1MB of cache is added Therefore, the high capacity of DRAM is irrelevant for use as cache memory, and its slow speed makes it a poor cache memory type D, SRAM requires a constant power refresh, is incorrect It is DRAM that requires a constant refresh C RDRAM is not supported by the processor in this case RDRAM uses special RIMM slots that weren t yet available when motherboards were being designed for the Pentium processor Due to the timing of the release of these two technologies, it is very unlikely that a motherboard would have been manufactured that supported a processor that old and a RAM technology that new A is incorrect because it says that RDRAM is intended for use by video cards, not processors RDRAM is actually a type of system RAM, not a video RAM technology B is incorrect because it suggests that the computer already has the maximum accessible RAM capacity However, Pentium processors have a 32-bit memory address bus, so they can access up to 4GB of RAM D is incorrect because it suggests telling her to install the RDRAM However, as discussed, the motherboard probably doesn t support RDRAM, and it is unlikely that the appropriate RIMM slots are even present D There are not enough modules installed The Rambus channel requires that all sockets be populated with either a RIMM (at least one) module or a C-RIMM In this case, you would have to add two C-RIMMS to the empty slots.

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