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operating at vGS = 1 V and a very small vDS Find a rDS b vGS at which rDS is half of its value in (a)

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common-source ampli er stage Determine the DC operating point and verify that the device is operating in the saturation region IDSS R1 RD RL RSS = 1125 mA VT = 15 V = 132 M R2 = 22 M =4k RS = 4 k = 13 k C = 047 F = 07 k VDD = 12 V

operated in the ohmic region, with vDS = 04 V and VT = 32 V The effective resistance of the channel is given by RDS = 500/(VGS 32) Find iD when vGS = 5 V, RDS = 500 , and vGD = 4 V

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operating in the ohmic region, with vGS = 1 V, vDS = 005 V, and iD = 03 mA Find iD if a vGS = 1 V, vDS = 008 V b vGS = 0 V, vDS = 01 V c vGS = 32 V, vDS = 006 V VT = 25 V has its source grounded and a 4-VDC source connected to the gate Find the operating region of the device if a vD = 05 V b vD = 15 V

ii C + RSS Vi + V _S _

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Postreplicative repair is part of a cell reaction called the SOS response When an E coli cell is exposed to excessive quantities of UV light, other mutagens, or agents that damage DNA (such as alkylating or cross-linking agents), or when DNA replication is inhibited, gaps are created in the DNA In the presence of this single-stranded DNA, the RecA protein interacts with the LexA protein, the product of the lexA gene The LexA protein normally represses about eighteen genes, including itself The other genes include recA, uvrA, uvrB, and uvrD; two genes that inhibit cell division, sulA and sulB; and several others Each of these genes has a consensus sequence in its promoter called the SOS box: 5 -CTGX10CAG-3 (where X10 refers to any ten bases) The LexA protein normally binds at the SOS box, limiting the transcription of these genes.

+ VDD _

When single-stranded DNA activates RecA, RecA interacts with the LexA protein to trigger the autocatalytic properties of LexA ( g 1237) Transcription then follows from all the genes having an SOS box The two inhibitors of cell division, the products of the sulA and sulB genes, presumably increase the amount of time the cell has to repair the damage before the next round of DNA replication Eventually, the DNA damage is repaired There is no single-stranded DNA to activate RecA, and, therefore, LexA is no longer destroyed LexA again represses the suite of proteins involved in the SOS response, and the SOS response is over Table 125 summarizes some of the enzymes and proteins involved in DNA repair As we will mention in chapter 14, prophage can be induced into vegetative growth by UV light This is another effect of the SOS response.

VT = 4 V, iD = 1 mA when vGS = vDS = 6 V Neglecting the dependence of iD on vDS in saturation, nd the value of iD for vGS = 5 V VT = 15 V, k = 04 mA/V 2 Now if vG is a pulse with 0 V to 5 V, nd the voltage levels of the pulse signal at the drain output

common-source ampli er stage where the DC bias network in the gate circuit has already been replaced by its Th venin equivalent Determine the DC e

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